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Antidepressants study
raises questions

Greg Feldman, Ph.D.

Greg Feldman, Ph.D., an assistant professor of psychology at Simmons College in Massachusetts (photo by Tom Croke)

By Ami Albernaz

A dozen years ago, rumblings began that antidepressants perhaps really weren't as effective as people thought. A 1998 analysis of 38 manufacturer-sponsored studies found that although antidepressants did help people who were depressed, they offered little more boost than did a placebo. Four years later, another analysis, this time also including unpublished studies sent to the U.S. Food and Drug Administration, suggested antidepressants offered even less of an advantage than the minuscule benefit shown in the previous report.

The latest salvo came two months ago, when another analysis published in the Journal of the American Medical Association (JAMA) indicated that antidepressants had significant benefits only in the most severely depressed patients. Though the findings are raising questions for some about the faith long placed in antidepressant medications, others say they don't offer strong enough evidence for writing them off. [More]

 

 

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